Patent · US Active

Methods and compositions for macrophage polarization

US11512315B2 · kind B2 · utility

1Cited by

1References

9Claims

0Family size

Assignee

CODIAK BIOSCIENCES, INC. · US

Inventors

Sriram Sathyanarayanan · Lexington, US
Douglas E. Williams · Redmond, US
Dalia BURZYN · Newton, US
Adam Thomas BOUTIN · Cambridge, US
Sushrut KAMERKAR · Houston, US

Key dates

Filing date	Feb 12, 2019
Grant date	Nov 29, 2022
Priority date	—
Expiry date	Feb 12, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compositions and methods comprising extracellular vesicles comprising nucleic acid that target genes, leading to macrophage polarization of tumor associated macrophages. In certain embodiments, disclosed herein are methods and compositions for increasing macrophage polarization for the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.