Emulsion based drug screening
US11512337B2 · kind B2 · utility
4Cited by
44References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 12, 2021 |
| Grant date | Nov 29, 2022 |
| Priority date | — |
| Expiry date | Aug 26, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/106
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods and systems for drug screening by segregating single cells into droplets simultaneously and providing candidate compound to the single cells to measure cellular response. Methods of the present invention combine template particles with a plurality of single cells in a tube, generate in the tube monodispersed droplets simultaneously that encapsulate a single one of the template particles and single one of the single cells, provide to the single cells one or more candidate compounds, and measure a cellular response to the one or more candidate compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.