Methods and apparatus for magnetic multi-bead assays
US11513115B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 2017 |
| Grant date | Nov 29, 2022 |
| Priority date | — |
| Expiry date | Jun 1, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/323
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present application discloses methods and apparatus for detecting a complex including an analyte that include contacting a sample in a solution with a population of functionalized beads of a first type, which are magnetic functionalized beads and are functionalized to include a first moiety that associates with an analyte under suitable conditions, contacting the sample solution with a population of functionalized beads of a second type, which are functionalized to include a second moiety that associates with the analyte under suitable conditions, contact resulting in formation of a complex including one of the first type of functionalized bead, the analyte, and one of the second type of functionalized bead, and detecting the complex including the analyte by detecting magnetic fields produced by the magnetic functionalized bead and by detecting the functionalized bead of the second type associated with the analyte in the complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.