Restoring physiology in iron-deficient organisms using small molecules
US11517540B2 · kind B2 · utility
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Key dates
| Filing date | Jan 11, 2016 |
| Grant date | Dec 6, 2022 |
| Priority date | — |
| Expiry date | Jan 11, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter using a small molecule. For example, the method may increase transepithelial iron transport, or it may increase iron release. Additionally, the small molecule may be hinokitiol, or it may be selected from the group consisting of amphotericin B, calcimycin, nonactin, deferiprone, purpurogallin, and maltol. Also provided is a method of identifying a compound capable of treating a disease or condition characterized by a deficiency of or a defect in an iron transporter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.