Fucosyltransferase specific inhibition using fucose mimetics
US11517580B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Dec 29, 2020 |
| Grant date | Dec 6, 2022 |
| Priority date | — |
| Expiry date | Dec 29, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are compositions and methods for specific fucosyltransferase inhibition for treatment of a variety of diseases. The compositions of the invention comprise a glycomimetic of L-Fucose that selectively inhibits the generation of sialyl Lewis X by FTVI and FTVII but has no effect on the generation of Lewis X by FTIX.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.