Patent · US Active

Pyrrolobenzodiazepine antibody conjugates

US11517626B2 · kind B2 · utility

0Cited by

99References

13Claims

0Family size

Assignee

MedImmune Limited · US

Inventors

Philip Wilson Howard · London, GB
Elizabeth Dunny · Cambridge, GB
Luke Masterson · Cambridge, GB

Key dates

Filing date	Feb 10, 2017
Grant date	Dec 6, 2022
Priority date	—
Expiry date	Oct 28, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A conjugate of formula I: L-(DL)P (1)wherein L is a Ligand unit, DL is a Drug Linker unit of formula II:wherein either:(a) R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are bound; or(b) R11 is OH, and R10 is:p is an integer of from 1 to 20.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.