Patent · US Active

Multifunctional heteromultimeric constructs

US11518791B2 · kind B2 · utility

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0References

11Claims

0Family size

Assignees

LUXEMBOURG INSTITUTE OF HEALTH · LU
UNIVERSITÉ DE REIMS CHAMPAGNE-ARDENNE · FR

Inventors

Xavier Dervillez · Wincheringen, DE
Carole Devaux · Zoufftgen, FR
Jacques H.M. Cohen · Reims, FR

Key dates

Filing date	May 22, 2017
Grant date	Dec 6, 2022
Priority date	—
Expiry date	Dec 20, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/74
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.