Patent · US Active

Anti-ROR1 antibodies and methods of making and using thereof

US11518815B2 · kind B2 · utility

1Cited by
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11Claims
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Key dates

Filing dateJun 22, 2018
Grant dateDec 6, 2022
Priority date
Expiry dateOct 15, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The application provides anti-ROR1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.