Variants of porcine trypsin

US11518988B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Thomas Stillger · Frankfurt am Main, DE
• Sebastian Rissom · Hofheim, DE
• Claudia Feller · Leipzig, DE
• Andreas Vogel · Leipzig, DE

Key dates

• Filing date: Feb 22, 2019
• Grant date: Dec 6, 2022
• Expiry date: Feb 22, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y304/21004
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to polypeptide variants of porcine trypsin, to nucleic acid molecules encoding these variants, and to host cells comprising such nucleic acid molecules. It also relates to the use of these variants in methods for producing insulin. The invention further relates to the use of these variants as medicaments, as food ingredients, or as feed ingredients and to the use of these variants within a process of manufacturing a food ingredient or a feed ingredient.