Tumor-navigating, self-eradicating, trail-armed salmonella for precision cancer therapy
US11519007B2 · kind B2 · utility
0Cited by
1References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 20, 2020 |
| Grant date | Dec 6, 2022 |
| Priority date | — |
| Expiry date | Feb 20, 2040 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating, self-eradicating, and armed with TRAIL to trigger tumor cell apoptosis. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.