Patent · US Active

System, method, and computer program product for detecting neurodegeneration using differential tractography

US11523767B2 · kind B2 · utility

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21Claims
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Key dates

Filing dateJan 28, 2021
Grant dateDec 13, 2022
Priority date
Expiry dateJan 28, 2041

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16H10/40
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Described are a system, method, and computer program product for detecting neurodegeneration using differential tractography and treating neurological disorders accordingly. The method includes obtaining a first diffusion magnetic resonance imaging (MRI) scan of the brain of the patient and obtaining a plurality of diffusion MRI scans of a group of other brains. The method also includes generating a control diffusion MRI scan based on the plurality of diffusion MRI scans of the group of other brains. The method further includes determining a first anisotropy of first neural tracks of the first diffusion MRI scan and a second anisotropy of second neural tracks of the control diffusion MRI scan. The method further includes determining a differential by comparing the first anisotropy to the second anisotropy and identifying at least one neurological disorder based on the differential and a location of the first neural tracks in the brain of the patient.

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