Patent · US Active

Substituted pyrazolo[3,4-d]pyrimidines as RET kinase inhibitors

US11524963B2 · kind B2 · utility

0Cited by
82References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 18, 2019
Grant dateDec 13, 2022
Priority date
Expiry dateMay 22, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Provided herein are compounds of the Formula I: and tautomers and pharmaceutically acceptable salts and solvates thereof, wherein R1 and R2 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.