Purification of polymerase complexes
US11525124B2 · kind B2 · utility
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8Claims
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Assignee
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Key dates
| Filing date | May 11, 2020 |
| Grant date | Dec 13, 2022 |
| Priority date | — |
| Expiry date | Feb 25, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07007
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods for isolating polymerase complexes from a mixture of polymerase complex components. The polymerase complexes can comprise a nanopore to provide isolated nanopore sequencing complexes. The methods relate to the positive and negative isolation of the polymerase complexes and/or nanopore sequencing complexes. Also disclosed is a nucleic acid adaptor for isolating active polymerase complexes, polymerase complexes comprising the nucleic acid adaptor, and methods for isolating active polymerase complexes using the nucleic acid adaptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.