Patent · US Active

Modified globin proteins

US11529421B2 · kind B2 · utility

1Cited by

2References

19Claims

0Family size

Assignee

UNIVERSITY OF ESSEX ENTERPRISES LIMITED · GB

Inventors

Chris E. Cooper · Vancouver, CA
Brandon Reeder · Colchester, GB
Gary Silkstone · Colchester, GB

Key dates

Filing date	Dec 19, 2018
Grant date	Dec 20, 2022
Priority date	—
Expiry date	Dec 19, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/805
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Certain aspects of the present invention relate to modified hemoglobin proteins comprising at least one modification (e.g., at the thiol group of an exogenous amino acid residue) for homogenous conjugation of one or more polymeric moieties e.g. polyethylene glycol or derivatives thereof. Also included herein are methods of using such modified proteins and compositions comprising such proteins, e.g. in therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.