Preparation method of eicosapentaenoic acid ethyl ester
US11535583B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 5, 2022 |
| Grant date | Dec 27, 2022 |
| Priority date | — |
| Expiry date | Jan 5, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC11C3/003
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
A preparation method of eicosapentaenoic acid (EPA) ethyl ester is provided and relates to the field of EPA ethyl ester processing technologies. The preparation method includes: performing degumming and deacidification on a sardine crude oil to obtain a semi-refined sardine oil, performing esterification on the semi-refined sardine oil to obtain an esterified sardine oil and then performing winterization on the esterified sardine oil to thereby obtain an semi-refined esterified sardine oil, performing bleaching and deodorization on the semi-refined esterified sardine oil, and performing multi-stage distillation treatment. Finally, the sardine oil is purified by liquid chromatography to obtain the high purity EPA ethyl ester. The preparation method can improve a utilization rate of the sardine oil and obtain the high-purity EPA ethyl ester.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.