Patent · US Active

Dioxoloisoquinolinone derivatives and use thereof

US11535629B2 · kind B2 · utility

1Cited by
0References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 20, 2021
Grant dateDec 27, 2022
Priority date
Expiry dateMay 20, 2041

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed are novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts thereof, optical isomers, hydrates, and solvates thereof as well as uses thereof. More specifically, the novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts, optical isomers, hydrates, solvates show inhibition activity of EZH1 (Enhancer of zeste homolog 1) and/or EZH2 (Enhancer of zeste homolog 2) activity. Pharmaceutical compositions containing the compound is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.