Patent · US Active

Fusion constructs and methods of using thereof

US11535669B2 · kind B2 · utility

1Cited by

8References

15Claims

0Family size

Assignee

Precigen, Inc. · US

Inventors

Helen Sabzevari · Blacksburg, US
Simon METENOU · Germantown, US
ChangHung Chen · Blacksburg, US
Rutul Shah · Boyds, US

Key dates

Filing date	Jul 9, 2019
Grant date	Dec 27, 2022
Priority date	—
Expiry date	Apr 20, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/33
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein is a composition comprising a fusion protein or a fragment or a variant thereof comprising an anti-PD1 antibody or a fragment/variant thereof and a TGF-β trap. Provided herein is a composition comprising a fusion protein or a fragment thereof or a variant thereof comprising an anti-PD1 antibody or a fragment/variant thereof and a ADA2 polypeptide. Also provided herein are methods of using the composition in treating cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.