Patent · US Active

Method for automated non-invasive measurement of sperm motility and morphology and automated selection of a sperm with high DNA integrity

US11536643B2 · kind B2 · utility

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20Claims
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Key dates

Filing dateMay 21, 2019
Grant dateDec 27, 2022
Priority date
Expiry dateMay 21, 2039

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06T2207/30024
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method of automated measurement of motility and morphology parameters of the same single motile sperm. Automated motility and morphology measurements of the same single sperm are performed under different microscope magnifications. The same single motile sperm is automatically positioned and kept inside microscope field of view and in focus after magnification switch. A method of automated non-invasive measurement of sperm morphology parameters under high magnification of imaging. Sperm morphology parameters including subcellular structures are automatically measured without invasive sample staining. A method of automatically selecting sperms with normal motility and morphology and DNA integrity for infertility treatment.

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