Patent · US Active

Devices, systems, and methods for measuring biomarkers in biological fluids

US11536732B2 · kind B2 · utility

1Cited by
43References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 13, 2020
Grant dateDec 27, 2022
Priority date
Expiry dateJun 24, 2041

Classification

  • Technology area (CPC H)Electricity
  • CPC primaryH04W84/18
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Platforms for enzymatic assays for biomarkers, including systems, methods, and measuring devices by which a biomarker, such as creatinine, is measured using a small amount of biological fluid, such as blood, plasma, or serum. The measuring device or biosensor can be a test strip including a layered active component assembly positioned between two outer layers which enables multi-step enzymatic reactions operating in kinetic and/or endpoint (in which the reaction is allowed to near completion), and generally includes multiple layers with primary enzyme(s), coupling enzyme(s), and reagents to produce an optical signal correlated to the concentration of a biomarker in the sample. The test strip can be read using a portable optical reader coupled to a smart phone or tablet.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.