Patent · US Active

Method for digitally correcting an optical image of a sample by means of a microscope, and microscope

US11536939B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

LEICA MICROSYSTEMS CMS GMBH · DE

Inventors

Christian Schumann · Gießen, DE
Tobias Bauer · Königstein, DE

Key dates

Filing date	Oct 18, 2019
Grant date	Dec 27, 2022
Priority date	—
Expiry date	Oct 18, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/30024
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method is useable for digitally correcting an optical image of a sample by a microscope that has a cover slip covering the sample. The method includes: determining, by the microscope, an index of refraction of an optical medium bordering the cover slip, a tilt of the cover slip, and/or a thickness of the cover slip; ascertaining an imaging error to be corrected in the form of a pupil function based on the index of refraction of the optical medium, the tilt of the cover slip, and/or the thickness of the cover slip; carrying out imaging of the sample by the microscope; and digitally correcting image data captured by the imaging of the sample based on the pupil function.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.