Noncrushable pill formulations

US11541125B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Heather D. Maynard · Los Angeles, US
• Natalie Boehnke · Los Angeles, US
• Samantha J. Paluck · Los Angeles, US

Key dates

• Filing date: Dec 19, 2017
• Grant date: Jan 3, 2023
• Expiry date: Jun 9, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y304/21004
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Non-crushable pill formulations and methods of using the formulations are disclosed. A non-crushable pill formulation for preventing unintended use of a drug, comprising a polymer, the polymer forming a polymer backbone of the complex; cross-linkers, the cross-linkers connecting the polymer backbone through covalently bonding to form at least one inner cavity within the complex; and the drug, the drug being trapped either covalently or non-covalently in the at least one inner cavity within the complex, wherein the drug is protected from releasing outside of the complex.