Patent · US Active

Therapeutic compounds and methods of use thereof

US11542274B1 · kind B1 · utility

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6Claims
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Assignee

Inventors

Key dates

Filing dateSep 23, 2021
Grant dateJan 3, 2023
Priority date
Expiry dateSep 23, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There are provided new heterobifunctional agents designed to mediated formation of protein-protein dimers and promote ubiquitination of a protein of the dimer. Also provided are methods of synthesizing the agents, pharmaceutical formulations including the agents, and methods of using the agents to treat, ameliorate or cure diseases characterized by protein over-expression or malfunction.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.