Anti-CD3-binding domains and antibodies comprising them, and methods for their generation and use
US11542330B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | May 8, 2018 |
| Grant date | Jan 3, 2023 |
| Priority date | — |
| Expiry date | Sep 2, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Anti-CD3 binding domains and antibodies comprising them, including multispecific antibodies, with, inter alia, desirable T-cell activation and (re)directed target cell killing potency and developability, profiles are provided, as well as methods for their identification, isolation, and generation, and methods for their preparation and use. Reagents for identifying, isolating, selecting, generating and characterizing CD3 binding domains and antibodies comprising them are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.