Single nucleotide polymorphism marker related to Chinese horse short stature trait and use thereof

US11542562B2 · kind B2 · utility

Assignee

• Institute of Animal Science, Chinese Academy of Agricultural Sciences · CN

Inventors

• Yuehui MA · Beijing, CN
• Lin Jiang · Los Angeles, US
• Xuexue Liu · Beijing, CN
• Yabin Pu · Beijing, CN
• Yanli Zhang · San Jose, US

Key dates

• Filing date: Sep 2, 2020
• Grant date: Jan 3, 2023
• Expiry date: Feb 8, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/16
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a single nucleotide polymorphism (SNP) marker related to a Chinese horse short stature trait. The SNP molecular marker is located at the 501th position of a sequence shown in SEQ ID NO.1, polymorphism is G/A, and the SNP marker corresponds to base pair 18,205,998 on chromosome 8 in a horse. The SNP marker related to the Chinese horse short stature trait and use thereof provided by the present invention have the following advantages that: (1) the molecular marker is not restricted by the age, sex and the like of Chinese horses, is used in early breeding of the Chinese horses, performs accurate screening immediately at birth, and significantly promotes the breeding process of dominant pony varieties of the Chinese horse; (2) a method for detecting SNP of a Chinese horse TBX3 gene is accurate, reliable, and easy to operate.