Methods of treating and imaging tumor micrometastases using photoactive immunoconjugates
US11547300B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 2015 |
| Grant date | Jan 10, 2023 |
| Priority date | — |
| Expiry date | Mar 1, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for evaluating micrometastases in a tissue region of a subject are described. The methods include administering to the subject a detectably effective amount of a tumor-targeted photoactivatable immunoconjugate; allowing a sufficient amount of time for the tumor-targeted photoactivatable immunoconjugate to enter micrometastases in the tissue region; illuminating the tumor-targeted photoactivatable immunoconjugate; obtaining an image of the tissue region of the subject using a fluorescent imaging device, and evaluating the micrometastases in the tissue region by conducting algorithmic analysis of the image. Methods of treating micrometastases in a tissue region of a subject are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.