Patent · US Active

Methods of treating disorders associated with castor

US11547709B2 · kind B2 · utility

0Cited by

5References

19Claims

0Family size

Assignees

St. Jude Children's Research Hospital, Inc. · US
COA THERAPEUTICS, INC. · US

Inventors

Suzanne JACKOWSKI · Bartlett, US
Charles O. ROCK · Bartlett, US
Richard E. Lee · Cordova, US
Lalit Kumar SHARMA · South San Francisco, US
Mi Kyung Yun · Daejeon, KR
Chitra SUBRAMANIAN · Cordova, US
Rajendra Tangallapally · Collierville, US
Anne V. Edwards · San Mateo, US
Robert Zamboni · Rue du Bois des Loges, CA
T. Jagadeeswar Reddy · Le Sueur (Canton), CA
Jiuyu Liu · Beijing, CN

Key dates

Filing date	Dec 26, 2018
Grant date	Jan 10, 2023
Priority date	—
Expiry date	Apr 20, 2039

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P3/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.