Kinase inhibitor compounds and compositions and methods of use
US11547712B2 · kind B2 · utility
4Cited by
2References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2018 |
| Grant date | Jan 10, 2023 |
| Priority date | — |
| Expiry date | Nov 20, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to kinase inhibitor compounds having the following structure: or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where R1, R2, X, n, R3, Y, Z, R4, R5, R6, and = are as defined herein. The present invention also relates to compositions containing the kinase inhibitor compounds, methods of inhibiting activity of a kinase in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.