Preparation method of selenium-containing heterocyclic compounds

US11548862B2 · kind B2 · utility

Assignee

• Wenzhou University · CN

Inventors

• Miaochang Liu · Wenzhou, CN
• Liguo Lu · Wenzhou, CN
• Chuanli Chen · Wenzhou, CN
• Yunbing Zhou · Wenzhou, CN
• Huayue Wu · Wenzhou, CN

Key dates

• Filing date: Nov 16, 2021
• Grant date: Jan 10, 2023
• Expiry date: Nov 16, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D293/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A reaction of azacyclopropane derivative with elemental selenium and TMSCN to construct a selenium-containing heterocycle under metal-free and additive-free conditions is provided. The new strategy features no metal participation, no additive promotion, a wide substrate selection range and a good functional group compatibility, and provides an efficient and green approach to constructing a variety of selenium-containing heterocyclic compounds in a highly concise way.