Patent · US Active

1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor

US11554120B2 · kind B2 · utility

0Cited by

22References

13Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Yam B. Poudel · Fremont, US
Sanjeev Gangwar · Foster City, US
Liqi He · West Chester, US
Prasanna Sivaprakasam · Lawrenceville, US
Matthias Broekema · New Hope, US
Matthew Cox · Farmingdale, US
Christine M. Tarby · Lawrenceville, US
Qian Zhang · Sha Tin, CN
Naidu S. Chowdari · Sunnyvale, US

Key dates

Filing date	Jul 31, 2019
Grant date	Jan 17, 2023
Priority date	—
Expiry date	Nov 18, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.