MIC therapy for specific immunosuppression in transplantation

US11554139B2 · kind B2 · utility

Assignees

• TOLEROGENIXX GMBH · DE
• Universität Heidelberg · DE

Inventors

• Christian Morath · Heidelberg, DE
• Anita Schmitt · Bammental, DE
• Matthias Schaier · Heidelberg, DE
• Gerhard Opelz · Heidelberg, DE
• Peter Terness · Eppelheim, DE
• Christian Kleist · Neckargemünd, DE
• Volker Daniel · Heidelberg, DE
• Caner Süsal · Dossenheim, DE
• Michael Schmitt · Kansas City, US
• Martin Zeier · Gaiberg, DE

Key dates

• Filing date: May 17, 2019
• Grant date: Jan 17, 2023
• Expiry date: May 17, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2239/38
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to pharmaceutical compositions with isolated and treated whole blood cells or Peripheral Blood Mononuclear Cells (PBMCs) as well as such pharmaceutical compositions for use in the prevention and/or treatment of organ or cell graft rejection in a human graft recipient.