Patent · US Active

Micro-reaction system and method for preparing 2-methyl-4-amino-5-aminomethyl pyrimidine

US11554354B2 · kind B2 · utility

0Cited by

6References

10Claims

0Family size

Assignee

FUDAN UNIVERSITY · CN

Inventors

Fener CHEN · Shanghai, CN
Meifen JIANG · Shanghai, CN
Dang CHENG · Shanghai, CN
Minjie LIU · Shanghai, CN
Huashan HUANG · Shanghai, CN

Key dates

Filing date	Sep 3, 2021
Grant date	Jan 17, 2023
Priority date	—
Expiry date	Sep 3, 2041

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01J2219/00984
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

A micro-reaction system and a method for preparing 2-methyl-4-amino-5-aminomethyl pyrimidine. A Raney nickel catalyst is modified with formalin, and the modified Raney nickel catalyst is filled into a micro-channel reactor of the micro-reaction system. A substrate solution containing 2-methyl-4-amino-5-cyanopyrimidine and a base and hydrogen are transported to the micro-mixer and the micro-channel reactor in sequence for continuous catalytic hydrogenation to obtain 2-methyl-4-amino-5-aminomethyl pyrimidine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.