Patent · US Active

Micro reaction system and method for preparing 2-methyl-4-amino-5-cyanopyrimidine using same

US11554355B2 · kind B2 · utility

0Cited by

12References

11Claims

0Family size

Assignee

FUDAN UNIVERSITY · CN

Inventors

Fener CHEN · Shanghai, CN
Meifen JIANG · Shanghai, CN
Dang CHENG · Shanghai, CN
Minjie LIU · Shanghai, CN
Huashan HUANG · Shanghai, CN

Key dates

Filing date	Sep 3, 2021
Grant date	Jan 17, 2023
Priority date	—
Expiry date	Sep 3, 2041

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01J2219/00963
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed herein relates to pharmaceutical engineering, and more particularly to a micro reaction system and a method for preparing 2-methyl-4-amino-5-cyanopyrimidine using the same. An acetamidine hydrochloride solution and an (dimethylaminomethylene)malononitrile solution are separately pumped into the micro reaction system including a micromixer and an agitating microchannel reactor in communication at the same time for a continuous condensation-cyclization reaction to obtain 2-methyl-4-amino-5-cyanopyrimidine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.