Ceramide nanoliposomes, compositions and methods of using for immunotherapy
US11559504B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 1, 2018 |
| Grant date | Jan 24, 2023 |
| Priority date | — |
| Expiry date | Apr 17, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions for treating cancer are provided. Compositions comprising ceramide nanoliposomes are administered to a subject in need of such treatment. The composition administration also enhances immunotherapy. Further administering compositions in combination with tumor antigen specific T-cells, and/or compositions in combination with tumor antigen expressing cells, and/or said compositions in combination with antagonists of PD-1 provides for enhanced results. Administration of the compositions provides for effective treatment of tumors including regression and eradication of established tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.