Whole-cell cancer vaccines and methods for selection thereof
US11559574B2 · kind B2 · utility
0Cited by
4References
81Claims
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Assignee
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Key dates
| Filing date | Aug 23, 2018 |
| Grant date | Jan 24, 2023 |
| Priority date | — |
| Expiry date | Nov 18, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55522
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a modified human cancer cell comprising a recombinant polynucleotide encoding an allele of a human leukocyte antigen gene. The present invention also provides methods for selecting a whole-cell cancer vaccine for a subject having cancer and methods of treating cancer using whole-cell cancer vaccines of the present invention. In addition, the present invention provides a method of determining the HER2 status of a cell. Compositions and kits are also provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.