Heterocyclic inhibitors of monocarboxylate transporters
US11560389B2 · kind B2 · utility
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2References
5Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 23, 2020 |
| Grant date | Jan 24, 2023 |
| Priority date | — |
| Expiry date | Mar 14, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds of formulae A, B, and C as described herein that inhibit monocarboxylate transporters, such as MCT1 and MCT4. Compounds of the invention can be used for treatment of a condition in a patient, wherein the condition is characterized by the heightened activity or by the high prevalence of MCT1 and/or MCT4, such as cancer or type II diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.