Patent · US Active

Method for cleavage of solid phase-bound peptides from the solid phase

US11560402B2 · kind B2 · utility

0Cited by

3References

15Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Wolfgang Fiedler · Hemsbach, DE
Norbert Pleuss · Frankfurt am Main, DE
Bernd Henkel · Frankfurt am Main, DE
Manfred Gerken · Marburg, DE

Key dates

Filing date	Apr 10, 2019
Grant date	Jan 24, 2023
Priority date	—
Expiry date	Apr 10, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/605
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a method for the cleavage of a solid phase-bound polypeptide from the solid phase, the method comprising contacting the solid phase, to which the polypeptide is bound, with a composition consisting essentially of trifluoroacetic acid and 1,2-ethanedithiol, at a temperature in the range of about 23° C. to about 29° C.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.