Stable multispecific antibodies
US11560437B2 · kind B2 · utility
1Cited by
7References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2018 |
| Grant date | Jan 24, 2023 |
| Priority date | — |
| Expiry date | Feb 1, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to multispecific antibody constructs comprising Fab fragments having a particular set of mutations at the interface of the CH1 and CL domains, the mutations preventing heavy chain/light chain mispairing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.