Prevention of biofilm formation

US11560484B2 · kind B2 · utility

Assignees

• International Business Machines Corporation · US
• Institute of Bioengineering and Nanotechnology · SG

Inventors

• Amos Cahan · Dobbs Ferry, US
• Hariklia Deligianni · Alpine, US
• Xin Ding · Singapore, SG
• Mareva B. Fevre · San Jose, US
• James L. Hedrick · Pleasanton, US
• Pei-Yun S. Hsueh · New York, US
• Zhen Chang Liang · Singapore, SG
• Nathaniel H. Park · San Jose, US
• Theodore G. van Kessel · Millbrook, US
• Rudy J. Wojtecki · San Jose, US
• Yi Yan Yang · Singapore, SG

Key dates

• Filing date: Nov 8, 2019
• Grant date: Jan 24, 2023
• Expiry date: Jun 8, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09D179/02
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.