Hydroxy-substituted amino and ammonium derivatives and their medical use

US11564895B2 · kind B2 · utility

Assignee

• GRI BIO, INC. · US

Inventors

• Georg Schlechtingen · Dresden, DE
• Hans-Joachim Knolker · Dresden, DE
• Tim Friedrichson · Dresden, DE
• Gary Jennings · Dresden, DE
• Tobias Braxmeier · Gaggenau, DE

Key dates

• Filing date: Mar 19, 2021
• Grant date: Jan 31, 2023
• Expiry date: Mar 19, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C237/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula 1 or 2, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.