Patent · US Active

Gingko diterpene lactone composition

US11564904B2 · kind B2 · utility

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7Claims
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Key dates

Filing dateNov 13, 2018
Grant dateJan 31, 2023
Priority date
Expiry dateDec 1, 2038

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/0019
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A Ginkgo diterpene lactone composition is provided. The extract can lower the neurological function score of a cerebral ischemia-reperfusion rat, reduce the cerebral ischemia area and the water content after brain tissue edema, improve SOD activity, and decrease the MDA content. The composition can inhibit rabbit platelet aggregation induced by PAF and ADP inducers at different time points so as to reduce the maximum aggregation rate. In addition, experiments show that the effect of each monomer compound in the Ginkgo diterpene lactone composition is significantly increased at certain proportion.

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