Patent · US Active

Bioreactor with scaffolds

US11566215B2 · kind B2 · utility

0Cited by
155References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 30, 2020
Grant dateJan 31, 2023
Priority date
Expiry dateFeb 19, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12M29/10
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A bioreactor for culturing of cells is described. Screens suitable as a cell growth scaffold may comprise crossed fibers. Screens may be contained loosely in a screen holder, which in turn may be contained inside a manifold assembly. A lower manifold, screen holder and upper manifold may have identical or similar interior open cross-sections. Flow of liquid medium can occur upwardly through the array of screens, then flowing over a weir in the presence of an air pocket, and into a moat and a pump. The screen holder may have slots whose exterior-facing ligaments are rounded, and may have grooves whose interior-facing edges are rounded. These components may be located inside an incubator suitable to maintain desired environmental conditions and cleanliness.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.