Cell analysis using ChemFET sensor array-based systems
US11567036B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2019 |
| Grant date | Jan 31, 2023 |
| Priority date | — |
| Expiry date | May 22, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/4836
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Various cell analysis systems of the present teachings can measure the electrical and metabolic activity of single, living cells with subcellular addressability and simultaneous data acquisition for between about 10 cells to about 500,000 cells in a single analysis. Various sensor array devices of the present teachings can have sensor arrays with between 20 million to 660 million ChemFET sensors built into a massively paralleled array and can provide for simultaneous measurement of cells with data acquisition rates in the kilohertz (kHz) range. As various ChemFET sensor arrays of the present teachings can detect chemical analytes as well detect changes in cell membrane potential, various cell analysis systems of the present teachings also provide for the controlled chemical and electrical interrogation of cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.