Patent · US Active

Pyrazine compounds and uses thereof

US11571420B2 · kind B2 · utility

0Cited by
1References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 22, 2020
Grant dateFeb 7, 2023
Priority date
Expiry dateSep 22, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure novel pyrazine compounds targeting adenosine receptors (especially A1 and A2, particularly A2a). The present disclosure also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and use of the compounds in the treatment of adenosine receptor (AR) associated diseases, for example cancer such as NSCLC, RCC, prostate cancer, and breast cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.