Protein pores
US11572387B2 · kind B2 · utility
13Cited by
47References
12Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 2, 2018 |
| Grant date | Feb 7, 2023 |
| Priority date | — |
| Expiry date | Nov 22, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.