Patent · US Active

Method for prediction of acute rejection and renal allograft loss using pre-transplant transcriptomic signatures in recipient blood

US11572589B2 · kind B2 · utility

0Cited by

4References

8Claims

0Family size

Assignee

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · US

Inventors

Barbara Murphy · Pelham Manor, US
Weijia Zhang · Beijing, CN

Key dates

Filing date	Apr 16, 2019
Grant date	Feb 7, 2023
Priority date	—
Expiry date	Jul 4, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are gene signature sets expressed by kidney allograft recipients prior to transplant that determine the risk for acute rejection (AR) post-transplant and methods of using the gene signature sets for identifying renal allograft recipients at risk for acute rejection. Also disclosed herein are kits for use in the invention which comprise primer pairs for the gene signature sets.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.