Patent · US Active

Means and methods for single molecule peptide sequencing

US11573238B2 · kind B2 · utility

9Cited by

61References

17Claims

0Family size

Assignees

VIB VZW · BE
UNIVERSITEIT GENT · BE

Inventors

Nico Callewaert · Nevele, BE
Sven Eyckerman · Nazareth, BE
Simon Devos · Sint-Michiels, BE

Key dates

Filing date	Sep 28, 2018
Grant date	Feb 7, 2023
Priority date	—
Expiry date	Jan 18, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/6824
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to the field of biochemistry, more particularly to proteomics, more particularly to protein sequencing, even more particularly to single molecule peptide sequencing. The invention discloses methods for single molecule protein sequencing and/or amino acid identification using cleavage inducing agents which are not specific for one particular amino acid, cleave polypeptides step by step from the N-terminus onwards and provide information on the identity of the cleaved amino acids based on the reaction kinetics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.