Total cellular iron as a marker of cancer stem cells and uses thereof
US11573241B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Mar 8, 2017 |
| Grant date | Feb 7, 2023 |
| Priority date | — |
| Expiry date | May 1, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.