Triazacyclododecansulfonamide (“TCD”)-based protein secretion inhibitors
US11578055B2 · kind B2 · utility
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32Claims
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Inventor
Key dates
| Filing date | Mar 15, 2019 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Mar 15, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided herein are triazacyclododecansulfonamide (“TCD”)-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.