KDM1A inhibitors for the treatment of disease
US11578059B2 · kind B2 · utility
1Cited by
7References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 13, 2019 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Sep 22, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/107
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to compounds and methods which may be useful as inhibitors of KDM1A for the treatment or prevention of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation in cancer cells in a human or animal subject are also provided for treatment of disease such as acute myelogenous leukemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.