Oxadiazole derivatives as Rho-Kinase Inhibitors
US11578068B2 · kind B2 · utility
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23Claims
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Key dates
| Filing date | Dec 12, 2018 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Jul 4, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds of formula (I) inhibiting Rho Kinase that are oxidazole derivatives, processes for preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. Particularly the compounds of the invention may be useful in the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.